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A Contrastive Learning Pre-Training Method for Motif Occupancy Identification

Motif occupancy identification is a binary classification task predicting the binding of DNA motif instances to transcription factors, for which several sequence-based methods have been proposed. However, through direct training, these end-to-end methods are lack of biological interpretability withi...

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Detalles Bibliográficos
Autores principales: Lin, Ken, Quan, Xiongwen, Yin, Wenya, Zhang, Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103107/
https://www.ncbi.nlm.nih.gov/pubmed/35563090
http://dx.doi.org/10.3390/ijms23094699