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NUT Is a Driver of p300-Mediated Histone Hyperacetylation: From Spermatogenesis to Cancer

SIMPLE SUMMARY: The functional characterization of the BRD4-NUT fusion protein as the driver of the highly aggressive NUT Carcinoma is fundamental to the understanding of the mechanisms responsible for the genome-wide hyperacetylation of histones prior to their eviction during the final stages of sp...

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Detalles Bibliográficos
Autores principales: Rousseaux, Sophie, Reynoird, Nicolas, Khochbin, Saadi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103113/
https://www.ncbi.nlm.nih.gov/pubmed/35565363
http://dx.doi.org/10.3390/cancers14092234

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