A High-Efficiency AAV for Endothelial Cell Transduction Throughout the Central Nervous System

Endothelial cells have a crucial role in nervous system function, and mounting evidence points to endothelial impairment as a major contributor to a wide range of neurological diseases. However, tools to genetically interrogate these cells in vivo remain limited. Here, we describe AAV-BI30, a capsid...

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Detalles Bibliográficos
Autores principales: Krolak, Trevor, Chan, Ken Y., Kaplan, Luke, Huang, Qin, Wu, Jason, Zheng, Qingxia, Kozareva, Velina, Beddow, Thomas, Tobey, Isabelle G., Pacouret, Simon, Chen, Albert T., Chan, Yujia A., Ryvkin, Daniel, Gu, Chenghua, Deverman, Benjamin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103166/
https://www.ncbi.nlm.nih.gov/pubmed/35571675
http://dx.doi.org/10.1038/s44161-022-00046-4

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