Cargando…

Emerging antibody-based products for infectious diseases: Planning for metric ton manufacturing

This review focuses on the emerging monoclonal antibody market for infectious diseases and the metric ton scale manufacturing requirements to meet global demand. Increasing access to existing antibody-based products coupled with the unmet need in infectious disease will likely exceed the current exi...

Descripción completa

Detalles Bibliográficos
Autores principales: Whaley, Kevin J, Zeitlin, Larry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103258/
https://www.ncbi.nlm.nih.gov/pubmed/34259613
http://dx.doi.org/10.1080/21645515.2021.1930847
Descripción
Sumario:This review focuses on the emerging monoclonal antibody market for infectious diseases and the metric ton scale manufacturing requirements to meet global demand. Increasing access to existing antibody-based products coupled with the unmet need in infectious disease will likely exceed the current existing global manufacturing capacity. Further, the large numbers of individuals infected during epidemics such as the ongoing COVID-19 pandemic emphasizes the need to plan for metric ton manufacturing of monoclonal antibodies by expanding infrastructure and exploring alternative production systems.