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PTPRD and DCC Are Novel BACE1 Substrates Differentially Expressed in Alzheimer’s Disease: A Data Mining and Bioinformatics Study

The β-site Amyloid precursor protein Cleaving Enzyme 1 (BACE1) is an extensively studied therapeutic target for Alzheimer’s disease (AD), owing to its role in the production of neurotoxic amyloid beta (Aβ) peptides. However, despite numerous BACE1 inhibitors entering clinical trials, none have succe...

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Detalles Bibliográficos
Autores principales:	Taylor, Hannah A., Simmons, Katie J., Clavane, Eva M., Trevelyan, Christopher J., Brown, Jane M., Przemyłska, Lena, Watt, Nicole T., Matthews, Laura C., Meakin, Paul J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103286/ https://www.ncbi.nlm.nih.gov/pubmed/35562959 http://dx.doi.org/10.3390/ijms23094568

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