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Aquaponics-Derived Tilapia Skin Collagen for Biomaterials Development

Collagen is one of the most widely used biomaterials in health-related sectors. The industrial production of collagen mostly relies on its extraction from mammals, but several issues limited its use. In the last two decades, marine organisms attracted interest as safe, abundant, and alternative sour...

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Autores principales: Gallo, Nunzia, Natali, Maria Lucia, Quarta, Alessandra, Gaballo, Antonio, Terzi, Alberta, Sibillano, Teresa, Giannini, Cinzia, De Benedetto, Giuseppe Egidio, Lunetti, Paola, Capobianco, Loredana, Blasi, Federica Stella, Sicuro, Alessandro, Corallo, Angelo, Sannino, Alessandro, Salvatore, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103308/
https://www.ncbi.nlm.nih.gov/pubmed/35567034
http://dx.doi.org/10.3390/polym14091865
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author Gallo, Nunzia
Natali, Maria Lucia
Quarta, Alessandra
Gaballo, Antonio
Terzi, Alberta
Sibillano, Teresa
Giannini, Cinzia
De Benedetto, Giuseppe Egidio
Lunetti, Paola
Capobianco, Loredana
Blasi, Federica Stella
Sicuro, Alessandro
Corallo, Angelo
Sannino, Alessandro
Salvatore, Luca
author_facet Gallo, Nunzia
Natali, Maria Lucia
Quarta, Alessandra
Gaballo, Antonio
Terzi, Alberta
Sibillano, Teresa
Giannini, Cinzia
De Benedetto, Giuseppe Egidio
Lunetti, Paola
Capobianco, Loredana
Blasi, Federica Stella
Sicuro, Alessandro
Corallo, Angelo
Sannino, Alessandro
Salvatore, Luca
author_sort Gallo, Nunzia
collection PubMed
description Collagen is one of the most widely used biomaterials in health-related sectors. The industrial production of collagen mostly relies on its extraction from mammals, but several issues limited its use. In the last two decades, marine organisms attracted interest as safe, abundant, and alternative source for collagen extraction. In particular, the possibility to valorize the huge quantity of fish industry waste and byproducts as collagen source reinforced perception of fish collagen as eco-friendlier and particularly attractive in terms of profitability and cost-effectiveness. Especially fish byproducts from eco-sustainable aquaponics production allow for fish biomass with additional added value and controlled properties over time. Among fish species, Oreochromis niloticus is one of the most widely bred fish in large-scale aquaculture and aquaponics systems. In this work, type I collagen was extracted from aquaponics-raised Tilapia skin and characterized from a chemical, physical, mechanical, and biological point of view in comparison with a commercially available analog. Performed analysis confirmed that the proprietary process optimized for type I collagen extraction allowed to isolate pure native collagen and to preserve its native conformational structure. Preliminary cellular studies performed with mouse fibroblasts indicated its optimal biocompatibility. All data confirmed the eligibility of the extracted Tilapia-derived native type I collagen as a biomaterial for healthcare applications.
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spelling pubmed-91033082022-05-14 Aquaponics-Derived Tilapia Skin Collagen for Biomaterials Development Gallo, Nunzia Natali, Maria Lucia Quarta, Alessandra Gaballo, Antonio Terzi, Alberta Sibillano, Teresa Giannini, Cinzia De Benedetto, Giuseppe Egidio Lunetti, Paola Capobianco, Loredana Blasi, Federica Stella Sicuro, Alessandro Corallo, Angelo Sannino, Alessandro Salvatore, Luca Polymers (Basel) Article Collagen is one of the most widely used biomaterials in health-related sectors. The industrial production of collagen mostly relies on its extraction from mammals, but several issues limited its use. In the last two decades, marine organisms attracted interest as safe, abundant, and alternative source for collagen extraction. In particular, the possibility to valorize the huge quantity of fish industry waste and byproducts as collagen source reinforced perception of fish collagen as eco-friendlier and particularly attractive in terms of profitability and cost-effectiveness. Especially fish byproducts from eco-sustainable aquaponics production allow for fish biomass with additional added value and controlled properties over time. Among fish species, Oreochromis niloticus is one of the most widely bred fish in large-scale aquaculture and aquaponics systems. In this work, type I collagen was extracted from aquaponics-raised Tilapia skin and characterized from a chemical, physical, mechanical, and biological point of view in comparison with a commercially available analog. Performed analysis confirmed that the proprietary process optimized for type I collagen extraction allowed to isolate pure native collagen and to preserve its native conformational structure. Preliminary cellular studies performed with mouse fibroblasts indicated its optimal biocompatibility. All data confirmed the eligibility of the extracted Tilapia-derived native type I collagen as a biomaterial for healthcare applications. MDPI 2022-05-02 /pmc/articles/PMC9103308/ /pubmed/35567034 http://dx.doi.org/10.3390/polym14091865 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Gallo, Nunzia
Natali, Maria Lucia
Quarta, Alessandra
Gaballo, Antonio
Terzi, Alberta
Sibillano, Teresa
Giannini, Cinzia
De Benedetto, Giuseppe Egidio
Lunetti, Paola
Capobianco, Loredana
Blasi, Federica Stella
Sicuro, Alessandro
Corallo, Angelo
Sannino, Alessandro
Salvatore, Luca
Aquaponics-Derived Tilapia Skin Collagen for Biomaterials Development
title Aquaponics-Derived Tilapia Skin Collagen for Biomaterials Development
title_full Aquaponics-Derived Tilapia Skin Collagen for Biomaterials Development
title_fullStr Aquaponics-Derived Tilapia Skin Collagen for Biomaterials Development
title_full_unstemmed Aquaponics-Derived Tilapia Skin Collagen for Biomaterials Development
title_short Aquaponics-Derived Tilapia Skin Collagen for Biomaterials Development
title_sort aquaponics-derived tilapia skin collagen for biomaterials development
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103308/
https://www.ncbi.nlm.nih.gov/pubmed/35567034
http://dx.doi.org/10.3390/polym14091865
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