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Hippocampus-related cognitive disorders develop in the absence of epilepsy and ataxia in the heterozygous Cacna1a mutant mice tottering

CACNA1A-associated epilepsy and ataxia frequently accompany cognitive impairments as devastating co-morbidities. However, it is unclear whether the cognitive deficits are consequences secondary to the neurological symptoms elicited by CACNA1A mutations. To address this issue, Cacna1a mutant mice tot...

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Detalles Bibliográficos
Autores principales: Nakao, Akito, Hayashida, Katsumi, Ogura, Hiroo, Mori, Yasuo, Imoto, Keiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103357/
https://www.ncbi.nlm.nih.gov/pubmed/35548926
http://dx.doi.org/10.1080/19336950.2022.2072449