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Z-DNA binding protein 1 mediates necroptotic and apoptotic cell death pathways in murine astrocytes following herpes simplex virus-1 infection

BACKGROUND: The mechanisms by which glia respond to viral central nervous system (CNS) pathogens are now becoming apparent with the demonstration that microglia and astrocytes express an array of pattern recognition receptors that include intracellular RNA and DNA sensors. We have previously demonst...

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Detalles Bibliográficos
Autores principales: Jeffries, Austin M., Suptela, Alexander J., Marriott, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103380/
https://www.ncbi.nlm.nih.gov/pubmed/35549723
http://dx.doi.org/10.1186/s12974-022-02469-z