Synthesis and Investigation of the G-Quadruplex Binding Properties of Kynurenic Acid Derivatives with a Dihydroimidazoquinoline-3,5-dione Core

G-quadruplexes are secondary structures originating from nucleic acid regions rich in guanines, which are well known for their involvement in gene transcription and regulation and DNA damage repair. In recent studies from our group, kynurenic acid (KYNA) derivative 1 was synthesized and found to sha...

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Detalles Bibliográficos
Autores principales: Mazzini, Stefania, Princiotto, Salvatore, Musso, Loana, Passarella, Daniele, Beretta, Giovanni Luca, Perego, Paola, Dallavalle, Sabrina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103425/
https://www.ncbi.nlm.nih.gov/pubmed/35566141
http://dx.doi.org/10.3390/molecules27092791

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103425/
https://www.ncbi.nlm.nih.gov/pubmed/35566141
http://dx.doi.org/10.3390/molecules27092791

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