Overall survival analysis of > 65-year-old patients with breast cancer based on their molecular, clinicopathological and laboratory factors

INTRODUCTION: The objective of the present study was to characterize > 65-year-old patients with breast cancer according to clinicopathological, molecular and laboratory factors. METHODS: A total of 723 breast cancer patients, who had been diagnosed and treated during 2005–2019, were retrospectiv...

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Detalles Bibliográficos
Autores principales: Huszno, Joanna, Kolosza, Zofia, Mrochem-Kwarciak, Jolanta, Grzybowska, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2022
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103507/
https://www.ncbi.nlm.nih.gov/pubmed/35591831
http://dx.doi.org/10.5114/aoms/147736
Descripción
Sumario:INTRODUCTION: The objective of the present study was to characterize > 65-year-old patients with breast cancer according to clinicopathological, molecular and laboratory factors. METHODS: A total of 723 breast cancer patients, who had been diagnosed and treated during 2005–2019, were retrospectively reviewed. Patients > 65 years of age (92 patients) were compared with < 50-year-old women (306 patients). We analyzed 398 women from 723 patients. RESULTS: Overall survival analysis was conducted for both groups, separately and combined. Patients with BC aged > 65 years were characterized by G1-2, higher lymphocyte values, lower platelet (PLT) counts and lower NLR or PLR values than patients < 50 years of age. CONCLUSIONS: Age > 65 years is a negative prognostic factor independent of other factors.

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