Overall survival analysis of > 65-year-old patients with breast cancer based on their molecular, clinicopathological and laboratory factors

INTRODUCTION: The objective of the present study was to characterize > 65-year-old patients with breast cancer according to clinicopathological, molecular and laboratory factors. METHODS: A total of 723 breast cancer patients, who had been diagnosed and treated during 2005–2019, were retrospectiv...

Descripción completa

Detalles Bibliográficos
Autores principales: Huszno, Joanna, Kolosza, Zofia, Mrochem-Kwarciak, Jolanta, Grzybowska, Ewa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2022
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103507/
https://www.ncbi.nlm.nih.gov/pubmed/35591831
http://dx.doi.org/10.5114/aoms/147736
_version_ 1784707572665679872
author Huszno, Joanna
Kolosza, Zofia
Mrochem-Kwarciak, Jolanta
Grzybowska, Ewa
author_facet Huszno, Joanna
Kolosza, Zofia
Mrochem-Kwarciak, Jolanta
Grzybowska, Ewa
author_sort Huszno, Joanna
collection PubMed
description INTRODUCTION: The objective of the present study was to characterize > 65-year-old patients with breast cancer according to clinicopathological, molecular and laboratory factors. METHODS: A total of 723 breast cancer patients, who had been diagnosed and treated during 2005–2019, were retrospectively reviewed. Patients > 65 years of age (92 patients) were compared with < 50-year-old women (306 patients). We analyzed 398 women from 723 patients. RESULTS: Overall survival analysis was conducted for both groups, separately and combined. Patients with BC aged > 65 years were characterized by G1-2, higher lymphocyte values, lower platelet (PLT) counts and lower NLR or PLR values than patients < 50 years of age. CONCLUSIONS: Age > 65 years is a negative prognostic factor independent of other factors.
format Online
Article
Text
id pubmed-9103507
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Termedia Publishing House
record_format MEDLINE/PubMed
spelling pubmed-91035072022-05-18 Overall survival analysis of > 65-year-old patients with breast cancer based on their molecular, clinicopathological and laboratory factors Huszno, Joanna Kolosza, Zofia Mrochem-Kwarciak, Jolanta Grzybowska, Ewa Arch Med Sci Research Letter INTRODUCTION: The objective of the present study was to characterize > 65-year-old patients with breast cancer according to clinicopathological, molecular and laboratory factors. METHODS: A total of 723 breast cancer patients, who had been diagnosed and treated during 2005–2019, were retrospectively reviewed. Patients > 65 years of age (92 patients) were compared with < 50-year-old women (306 patients). We analyzed 398 women from 723 patients. RESULTS: Overall survival analysis was conducted for both groups, separately and combined. Patients with BC aged > 65 years were characterized by G1-2, higher lymphocyte values, lower platelet (PLT) counts and lower NLR or PLR values than patients < 50 years of age. CONCLUSIONS: Age > 65 years is a negative prognostic factor independent of other factors. Termedia Publishing House 2022-04-14 /pmc/articles/PMC9103507/ /pubmed/35591831 http://dx.doi.org/10.5114/aoms/147736 Text en Copyright: © 2022 Termedia & Banach https://creativecommons.org/licenses/by-nc-sa/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
spellingShingle Research Letter
Huszno, Joanna
Kolosza, Zofia
Mrochem-Kwarciak, Jolanta
Grzybowska, Ewa
Overall survival analysis of > 65-year-old patients with breast cancer based on their molecular, clinicopathological and laboratory factors
title Overall survival analysis of > 65-year-old patients with breast cancer based on their molecular, clinicopathological and laboratory factors
title_full Overall survival analysis of > 65-year-old patients with breast cancer based on their molecular, clinicopathological and laboratory factors
title_fullStr Overall survival analysis of > 65-year-old patients with breast cancer based on their molecular, clinicopathological and laboratory factors
title_full_unstemmed Overall survival analysis of > 65-year-old patients with breast cancer based on their molecular, clinicopathological and laboratory factors
title_short Overall survival analysis of > 65-year-old patients with breast cancer based on their molecular, clinicopathological and laboratory factors
title_sort overall survival analysis of > 65-year-old patients with breast cancer based on their molecular, clinicopathological and laboratory factors
topic Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103507/
https://www.ncbi.nlm.nih.gov/pubmed/35591831
http://dx.doi.org/10.5114/aoms/147736
work_keys_str_mv AT husznojoanna overallsurvivalanalysisof65yearoldpatientswithbreastcancerbasedontheirmolecularclinicopathologicalandlaboratoryfactors
AT koloszazofia overallsurvivalanalysisof65yearoldpatientswithbreastcancerbasedontheirmolecularclinicopathologicalandlaboratoryfactors
AT mrochemkwarciakjolanta overallsurvivalanalysisof65yearoldpatientswithbreastcancerbasedontheirmolecularclinicopathologicalandlaboratoryfactors
AT grzybowskaewa overallsurvivalanalysisof65yearoldpatientswithbreastcancerbasedontheirmolecularclinicopathologicalandlaboratoryfactors

Ejemplares similares