Utility of Lymphadenectomy in Prostate Cancer: Where Do We Stand?

The purpose of this review is to summarize the current knowledge on lymph node dissection (LND) in prostate cancer (PCa) patients undergoing radical prostatectomy (RP). Despite a growing body of evidence, the utility and therapeutic and prognostic value of such an approach, as well as the optimal ex...

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Autores principales: Małkiewicz, Bartosz, Kiełb, Paweł, Karwacki, Jakub, Czerwińska, Róża, Długosz, Paulina, Lemiński, Artur, Nowak, Łukasz, Krajewski, Wojciech, Szydełko, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103547/
https://www.ncbi.nlm.nih.gov/pubmed/35566471
http://dx.doi.org/10.3390/jcm11092343
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author Małkiewicz, Bartosz
Kiełb, Paweł
Karwacki, Jakub
Czerwińska, Róża
Długosz, Paulina
Lemiński, Artur
Nowak, Łukasz
Krajewski, Wojciech
Szydełko, Tomasz
author_facet Małkiewicz, Bartosz
Kiełb, Paweł
Karwacki, Jakub
Czerwińska, Róża
Długosz, Paulina
Lemiński, Artur
Nowak, Łukasz
Krajewski, Wojciech
Szydełko, Tomasz
author_sort Małkiewicz, Bartosz
collection PubMed
description The purpose of this review is to summarize the current knowledge on lymph node dissection (LND) in prostate cancer (PCa) patients undergoing radical prostatectomy (RP). Despite a growing body of evidence, the utility and therapeutic and prognostic value of such an approach, as well as the optimal extent of LND, remain unsolved issues. Although LND is the most accurate staging procedure, the direct therapeutic effect is still not evident from the current literature, which limits the possibility of establishing clear recommendations. This indicates the need for further robust and adequately designed high-quality clinical trials.
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spelling pubmed-91035472022-05-14 Utility of Lymphadenectomy in Prostate Cancer: Where Do We Stand? Małkiewicz, Bartosz Kiełb, Paweł Karwacki, Jakub Czerwińska, Róża Długosz, Paulina Lemiński, Artur Nowak, Łukasz Krajewski, Wojciech Szydełko, Tomasz J Clin Med Review The purpose of this review is to summarize the current knowledge on lymph node dissection (LND) in prostate cancer (PCa) patients undergoing radical prostatectomy (RP). Despite a growing body of evidence, the utility and therapeutic and prognostic value of such an approach, as well as the optimal extent of LND, remain unsolved issues. Although LND is the most accurate staging procedure, the direct therapeutic effect is still not evident from the current literature, which limits the possibility of establishing clear recommendations. This indicates the need for further robust and adequately designed high-quality clinical trials. MDPI 2022-04-22 /pmc/articles/PMC9103547/ /pubmed/35566471 http://dx.doi.org/10.3390/jcm11092343 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Małkiewicz, Bartosz
Kiełb, Paweł
Karwacki, Jakub
Czerwińska, Róża
Długosz, Paulina
Lemiński, Artur
Nowak, Łukasz
Krajewski, Wojciech
Szydełko, Tomasz
Utility of Lymphadenectomy in Prostate Cancer: Where Do We Stand?
title Utility of Lymphadenectomy in Prostate Cancer: Where Do We Stand?
title_full Utility of Lymphadenectomy in Prostate Cancer: Where Do We Stand?
title_fullStr Utility of Lymphadenectomy in Prostate Cancer: Where Do We Stand?
title_full_unstemmed Utility of Lymphadenectomy in Prostate Cancer: Where Do We Stand?
title_short Utility of Lymphadenectomy in Prostate Cancer: Where Do We Stand?
title_sort utility of lymphadenectomy in prostate cancer: where do we stand?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103547/
https://www.ncbi.nlm.nih.gov/pubmed/35566471
http://dx.doi.org/10.3390/jcm11092343
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