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NVCL-Based Hydrogels and Composites for Biomedical Applications: Progress in the Last Ten Years

Hydrogels consist of three-dimensionally crosslinked polymeric chains, are hydrophilic, have the ability to absorb other molecules in their structure and are relatively easy to obtain. However, in order to improve some of their properties, usually mechanical, or to provide them with some physical, c...

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Detalles Bibliográficos
Autores principales: Gonzalez-Urias, Alejandra, Licea-Claverie, Angel, Sañudo-Barajas, J. Adriana, González-Ayón, Mirian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103572/
https://www.ncbi.nlm.nih.gov/pubmed/35563114
http://dx.doi.org/10.3390/ijms23094722
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author Gonzalez-Urias, Alejandra
Licea-Claverie, Angel
Sañudo-Barajas, J. Adriana
González-Ayón, Mirian A.
author_facet Gonzalez-Urias, Alejandra
Licea-Claverie, Angel
Sañudo-Barajas, J. Adriana
González-Ayón, Mirian A.
author_sort Gonzalez-Urias, Alejandra
collection PubMed
description Hydrogels consist of three-dimensionally crosslinked polymeric chains, are hydrophilic, have the ability to absorb other molecules in their structure and are relatively easy to obtain. However, in order to improve some of their properties, usually mechanical, or to provide them with some physical, chemical or biological characteristics, hydrogels have been synthesized combined with other synthetic or natural polymers, filled with inorganic nanoparticles, metals, and even polymeric nanoparticles, giving rise to composite hydrogels. In general, different types of hydrogels have been synthesized; however, in this review, we refer to those obtained from the thermosensitive polymer poly(N-vinylcaprolactam) (PNVCL) and we focus on the definition, properties, synthesis techniques, nanomaterials used as fillers in composites and mainly applications of PNVCL-based hydrogels in the biomedical area. This type of material has great potential in biomedical applications such as drug delivery systems, tissue engineering, as antimicrobials and in diagnostic and bioimaging.
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spelling pubmed-91035722022-05-14 NVCL-Based Hydrogels and Composites for Biomedical Applications: Progress in the Last Ten Years Gonzalez-Urias, Alejandra Licea-Claverie, Angel Sañudo-Barajas, J. Adriana González-Ayón, Mirian A. Int J Mol Sci Review Hydrogels consist of three-dimensionally crosslinked polymeric chains, are hydrophilic, have the ability to absorb other molecules in their structure and are relatively easy to obtain. However, in order to improve some of their properties, usually mechanical, or to provide them with some physical, chemical or biological characteristics, hydrogels have been synthesized combined with other synthetic or natural polymers, filled with inorganic nanoparticles, metals, and even polymeric nanoparticles, giving rise to composite hydrogels. In general, different types of hydrogels have been synthesized; however, in this review, we refer to those obtained from the thermosensitive polymer poly(N-vinylcaprolactam) (PNVCL) and we focus on the definition, properties, synthesis techniques, nanomaterials used as fillers in composites and mainly applications of PNVCL-based hydrogels in the biomedical area. This type of material has great potential in biomedical applications such as drug delivery systems, tissue engineering, as antimicrobials and in diagnostic and bioimaging. MDPI 2022-04-25 /pmc/articles/PMC9103572/ /pubmed/35563114 http://dx.doi.org/10.3390/ijms23094722 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Gonzalez-Urias, Alejandra
Licea-Claverie, Angel
Sañudo-Barajas, J. Adriana
González-Ayón, Mirian A.
NVCL-Based Hydrogels and Composites for Biomedical Applications: Progress in the Last Ten Years
title NVCL-Based Hydrogels and Composites for Biomedical Applications: Progress in the Last Ten Years
title_full NVCL-Based Hydrogels and Composites for Biomedical Applications: Progress in the Last Ten Years
title_fullStr NVCL-Based Hydrogels and Composites for Biomedical Applications: Progress in the Last Ten Years
title_full_unstemmed NVCL-Based Hydrogels and Composites for Biomedical Applications: Progress in the Last Ten Years
title_short NVCL-Based Hydrogels and Composites for Biomedical Applications: Progress in the Last Ten Years
title_sort nvcl-based hydrogels and composites for biomedical applications: progress in the last ten years
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103572/
https://www.ncbi.nlm.nih.gov/pubmed/35563114
http://dx.doi.org/10.3390/ijms23094722
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