Myoglobin Interaction with Lactate Rapidly Releases Oxygen: Studies on Binding Thermodynamics, Spectroscopy, and Oxygen Kinetics

Myoglobin (Mb)-mediated oxygen (O(2)) delivery and dissolved O(2) in the cytosol are two major sources that support oxidative phosphorylation. During intense exercise, lactate (LAC) production is elevated in skeletal muscles as a consequence of insufficient intracellular O(2) supply. The latter resu...

Descripción completa

Detalles Bibliográficos
Autores principales: Adepu, Kiran Kumar, Bhandari, Dipendra, Anishkin, Andriy, Adams, Sean H., Chintapalli, Sree V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103699/
https://www.ncbi.nlm.nih.gov/pubmed/35563138
http://dx.doi.org/10.3390/ijms23094747

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103699/
https://www.ncbi.nlm.nih.gov/pubmed/35563138
http://dx.doi.org/10.3390/ijms23094747

Ejemplares similares