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Myoglobin Interaction with Lactate Rapidly Releases Oxygen: Studies on Binding Thermodynamics, Spectroscopy, and Oxygen Kinetics
Myoglobin (Mb)-mediated oxygen (O(2)) delivery and dissolved O(2) in the cytosol are two major sources that support oxidative phosphorylation. During intense exercise, lactate (LAC) production is elevated in skeletal muscles as a consequence of insufficient intracellular O(2) supply. The latter resu...
Autores principales: | Adepu, Kiran Kumar, Bhandari, Dipendra, Anishkin, Andriy, Adams, Sean H., Chintapalli, Sree V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103699/ https://www.ncbi.nlm.nih.gov/pubmed/35563138 http://dx.doi.org/10.3390/ijms23094747 |
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