The human antibody sequence space and structural design of the V, J regions, and CDRH3 with Rosetta

The human adaptive immune response enables the targeting of epitopes on pathogens with high specificity. Infection with a pathogen induces somatic hyper-mutation and B-cell selection processes that govern the shape and diversity of the antibody sequence landscape. To date, even the largest immunome...

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Detalles Bibliográficos
Autores principales: Schmitz, Samuel, Schmitz, Emily A., Crowe, James E., Meiler, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103704/
https://www.ncbi.nlm.nih.gov/pubmed/35544469
http://dx.doi.org/10.1080/19420862.2022.2068212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103704/
https://www.ncbi.nlm.nih.gov/pubmed/35544469
http://dx.doi.org/10.1080/19420862.2022.2068212

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