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The human antibody sequence space and structural design of the V, J regions, and CDRH3 with Rosetta
The human adaptive immune response enables the targeting of epitopes on pathogens with high specificity. Infection with a pathogen induces somatic hyper-mutation and B-cell selection processes that govern the shape and diversity of the antibody sequence landscape. To date, even the largest immunome...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103704/ https://www.ncbi.nlm.nih.gov/pubmed/35544469 http://dx.doi.org/10.1080/19420862.2022.2068212 |