Cargando…
Overexpression of Renin-B Induces Warburg-like Effects That Are Associated with Increased AKT/mTOR Signaling
The classical secretory renin-a is known to be involved in angiotensin generation, thereby regulating not only blood pressure, but also promoting oxidative stress as well as apoptotic and necrotic cell death. In contrast, another cytosolic renin isoform named renin-b has been described, exerting pro...
Autores principales: | Golchert, Janine, Staar, Doreen, Bennewitz, Jonathan, Hartmann, Miriam, Hoffmann, Nadin, Ameling, Sabine, Völker, Uwe, Peters, Jörg, Wanka, Heike |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103744/ https://www.ncbi.nlm.nih.gov/pubmed/35563765 http://dx.doi.org/10.3390/cells11091459 |
Ejemplares similares
-
Overexpression of Transcripts Coding for Renin-b but Not for Renin-a Reduce Oxidative Stress and Increase Cardiomyoblast Survival under Starvation Conditions
por: Wanka, Heike, et al.
Publicado: (2021) -
Angiotensin dependent and angiotensin independent protective effects of renin-b in H9c2 cells after anoxia
por: Wanka, Heike, et al.
Publicado: (2020) -
An alternative renin isoform is cardioprotective by modulating mitochondrial metabolism
por: Wanka, Heike, et al.
Publicado: (2018) -
Non-secretory renin reduces oxidative stress and increases cardiomyoblast survival during glucose and oxygen deprivation
por: Wanka, Heike, et al.
Publicado: (2020) -
A renin transcript lacking exon 1 encodes for a non-secretory intracellular renin that increases aldosterone production in transgenic rats
por: Peters, Jörg, et al.
Publicado: (2008)