A Tumor-Homing Peptide Platform Enhances Drug Solubility, Improves Blood–Brain Barrier Permeability and Targets Glioblastoma

SIMPLE SUMMARY: Glioblastoma (GBM) is a fatal and incurable brain cancer, and current treatment options have demonstrated limited success. Here, we describe the use of a dg-Bcan-Targeting-Peptide (BTP-7) that has BBB-penetrating properties and targets GBM. Conjugation of BTP-7 to an insoluble anti-c...

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Detalles Bibliográficos
Autores principales: Cho, Choi-Fong, Farquhar, Charlotte E., Fadzen, Colin M., Scott, Benjamin, Zhuang, Pei, von Spreckelsen, Niklas, Loas, Andrei, Hartrampf, Nina, Pentelute, Bradley L., Lawler, Sean E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103942/
https://www.ncbi.nlm.nih.gov/pubmed/35565337
http://dx.doi.org/10.3390/cancers14092207

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103942/
https://www.ncbi.nlm.nih.gov/pubmed/35565337
http://dx.doi.org/10.3390/cancers14092207

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