High-Throughput Profiling of Colorectal Cancer Liver Metastases Reveals Intra- and Inter-Patient Heterogeneity in the EGFR and WNT Pathways Associated with Clinical Outcome

SIMPLE SUMMARY: Tumor heterogeneity can greatly influence therapy outcome and patient survival. In this study, we aimed at unraveling inter- and intra-patient heterogeneity of colorectal cancer liver metastases (CRLM). To this end, we comprehensively characterized CRLM using state-of-the-art high-th...

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Detalles Bibliográficos
Autores principales: Menck, Kerstin, Wlochowitz, Darius, Wachter, Astrid, Conradi, Lena-Christin, Wolff, Alexander, Scheel, Andreas H., Korf, Ulrike, Wiemann, Stefan, Schildhaus, Hans-Ulrich, Bohnenberger, Hanibal, Wingender, Edgar, Pukrop, Tobias, Homayounfar, Kia, Beißbarth, Tim, Bleckmann, Annalen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9104154/
https://www.ncbi.nlm.nih.gov/pubmed/35565214
http://dx.doi.org/10.3390/cancers14092084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9104154/
https://www.ncbi.nlm.nih.gov/pubmed/35565214
http://dx.doi.org/10.3390/cancers14092084

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