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Glucose Starvation or Pyruvate Dehydrogenase Activation Induce a Broad, ERK5-Mediated, Metabolic Remodeling Leading to Fatty Acid Oxidation
Cells have metabolic flexibility that allows them to adapt to changes in substrate availability. Two highly relevant metabolites are glucose and fatty acids (FA), and hence, glycolysis and fatty acid oxidation (FAO) are key metabolic pathways leading to energy production. Both pathways affect each o...
Autores principales: | Khan, Abrar Ul Haq, Salehi, Hamideh, Alexia, Catherine, Valdivielso, Jose M., Bozic, Milica, Lopez-Mejia, Isabel C., Fajas, Lluis, Gerbal-Chaloin, Sabine, Daujat-Chavanieu, Martine, Gitenay, Delphine, Villalba, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9104157/ https://www.ncbi.nlm.nih.gov/pubmed/35563698 http://dx.doi.org/10.3390/cells11091392 |
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