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Glucose Starvation or Pyruvate Dehydrogenase Activation Induce a Broad, ERK5-Mediated, Metabolic Remodeling Leading to Fatty Acid Oxidation

Cells have metabolic flexibility that allows them to adapt to changes in substrate availability. Two highly relevant metabolites are glucose and fatty acids (FA), and hence, glycolysis and fatty acid oxidation (FAO) are key metabolic pathways leading to energy production. Both pathways affect each o...

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Detalles Bibliográficos
Autores principales: Khan, Abrar Ul Haq, Salehi, Hamideh, Alexia, Catherine, Valdivielso, Jose M., Bozic, Milica, Lopez-Mejia, Isabel C., Fajas, Lluis, Gerbal-Chaloin, Sabine, Daujat-Chavanieu, Martine, Gitenay, Delphine, Villalba, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9104157/
https://www.ncbi.nlm.nih.gov/pubmed/35563698
http://dx.doi.org/10.3390/cells11091392

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