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Quantitative Systems Pharmacology and Biased Agonism at Opioid Receptors: A Potential Avenue for Improved Analgesics

Chronic pain is debilitating and represents a significant burden in terms of personal and socio-economic costs. Although opioid analgesics are widely used in chronic pain treatment, many patients report inadequate pain relief or relevant adverse effects, highlighting the need to develop analgesics w...

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Detalles Bibliográficos
Autores principales: Bedini, Andrea, Cuna, Elisabetta, Baiula, Monica, Spampinato, Santi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9104178/
https://www.ncbi.nlm.nih.gov/pubmed/35563502
http://dx.doi.org/10.3390/ijms23095114