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How Does Starch Structure Impact Amylolysis? Review of Current Strategies for Starch Digestibility Study
In vitro digestibility of starch is a common analysis in human nutrition research, and generally consists of performing the hydrolysis of starch by α-amylase in specific conditions. Similar in vitro assays are also used in other research fields, where different methods can be used. Overall, the in v...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9104245/ https://www.ncbi.nlm.nih.gov/pubmed/35563947 http://dx.doi.org/10.3390/foods11091223 |
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author | Wang, Yuzi Ral, Jean-Philippe Saulnier, Luc Kansou, Kamal |
author_facet | Wang, Yuzi Ral, Jean-Philippe Saulnier, Luc Kansou, Kamal |
author_sort | Wang, Yuzi |
collection | PubMed |
description | In vitro digestibility of starch is a common analysis in human nutrition research, and generally consists of performing the hydrolysis of starch by α-amylase in specific conditions. Similar in vitro assays are also used in other research fields, where different methods can be used. Overall, the in vitro hydrolysis of native starch is a bridge between all of these methods. In this literature review, we examine the use of amylolysis assays in recent publications investigating the complex starch structure-amylolysis relation. This review is divided in two parts: (1) a brief review of the factors influencing the hydrolysis of starch and (2) a systematic review of the experimental designs and methods used in publications for the period 2016–2020. The latter reports on starch materials, factors investigated, characterization of the starch hydrolysis kinetics and data analysis techniques. This review shows that the dominant research strategy favors the comparison between a few starch samples most frequently described through crystallinity, granule type, amylose and chain length distribution with marked characteristics. This strategy aims at circumventing the multifactorial aspect of the starch digestion mechanism by focusing on specific features. An alternative strategy relies on computational approaches such as multivariate statistical analysis and machine learning techniques to decipher the role of each factor on amylolysis. While promising to address complexity, the limited use of a computational approach can be explained by the small size of the experimental datasets in most publications. This review shows that key steps towards the production of larger datasets are already available, in particular the generalization of rapid hydrolysis assays and the development of quantification approaches for most analytical results. |
format | Online Article Text |
id | pubmed-9104245 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-91042452022-05-14 How Does Starch Structure Impact Amylolysis? Review of Current Strategies for Starch Digestibility Study Wang, Yuzi Ral, Jean-Philippe Saulnier, Luc Kansou, Kamal Foods Systematic Review In vitro digestibility of starch is a common analysis in human nutrition research, and generally consists of performing the hydrolysis of starch by α-amylase in specific conditions. Similar in vitro assays are also used in other research fields, where different methods can be used. Overall, the in vitro hydrolysis of native starch is a bridge between all of these methods. In this literature review, we examine the use of amylolysis assays in recent publications investigating the complex starch structure-amylolysis relation. This review is divided in two parts: (1) a brief review of the factors influencing the hydrolysis of starch and (2) a systematic review of the experimental designs and methods used in publications for the period 2016–2020. The latter reports on starch materials, factors investigated, characterization of the starch hydrolysis kinetics and data analysis techniques. This review shows that the dominant research strategy favors the comparison between a few starch samples most frequently described through crystallinity, granule type, amylose and chain length distribution with marked characteristics. This strategy aims at circumventing the multifactorial aspect of the starch digestion mechanism by focusing on specific features. An alternative strategy relies on computational approaches such as multivariate statistical analysis and machine learning techniques to decipher the role of each factor on amylolysis. While promising to address complexity, the limited use of a computational approach can be explained by the small size of the experimental datasets in most publications. This review shows that key steps towards the production of larger datasets are already available, in particular the generalization of rapid hydrolysis assays and the development of quantification approaches for most analytical results. MDPI 2022-04-24 /pmc/articles/PMC9104245/ /pubmed/35563947 http://dx.doi.org/10.3390/foods11091223 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Systematic Review Wang, Yuzi Ral, Jean-Philippe Saulnier, Luc Kansou, Kamal How Does Starch Structure Impact Amylolysis? Review of Current Strategies for Starch Digestibility Study |
title | How Does Starch Structure Impact Amylolysis? Review of Current Strategies for Starch Digestibility Study |
title_full | How Does Starch Structure Impact Amylolysis? Review of Current Strategies for Starch Digestibility Study |
title_fullStr | How Does Starch Structure Impact Amylolysis? Review of Current Strategies for Starch Digestibility Study |
title_full_unstemmed | How Does Starch Structure Impact Amylolysis? Review of Current Strategies for Starch Digestibility Study |
title_short | How Does Starch Structure Impact Amylolysis? Review of Current Strategies for Starch Digestibility Study |
title_sort | how does starch structure impact amylolysis? review of current strategies for starch digestibility study |
topic | Systematic Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9104245/ https://www.ncbi.nlm.nih.gov/pubmed/35563947 http://dx.doi.org/10.3390/foods11091223 |
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