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Epidemiology and Clinical Characteristics Based on the Rome III and IV Criteria of Japanese Patients with Functional Dyspepsia

The subtypes of functional dyspepsia (FD) differ depending on whether the Rome III criteria or the Rome IV criteria are used. We investigated the ability to diagnose FD patients using the Rome III and IV criteria. The subtypes of FD were evaluated using the Rome questionnaire. The Gastrointestinal S...

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Autores principales: Aono, Sota, Tomita, Toshihiko, Tozawa, Katsuyuki, Morishita, Daisuke, Nakai, Keisuke, Okugawa, Takuya, Fukushima, Masashi, Oshima, Tadayuki, Fukui, Hirokazu, Miwa, Hiroto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9104296/
https://www.ncbi.nlm.nih.gov/pubmed/35566472
http://dx.doi.org/10.3390/jcm11092342
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author Aono, Sota
Tomita, Toshihiko
Tozawa, Katsuyuki
Morishita, Daisuke
Nakai, Keisuke
Okugawa, Takuya
Fukushima, Masashi
Oshima, Tadayuki
Fukui, Hirokazu
Miwa, Hiroto
author_facet Aono, Sota
Tomita, Toshihiko
Tozawa, Katsuyuki
Morishita, Daisuke
Nakai, Keisuke
Okugawa, Takuya
Fukushima, Masashi
Oshima, Tadayuki
Fukui, Hirokazu
Miwa, Hiroto
author_sort Aono, Sota
collection PubMed
description The subtypes of functional dyspepsia (FD) differ depending on whether the Rome III criteria or the Rome IV criteria are used. We investigated the ability to diagnose FD patients using the Rome III and IV criteria. The subtypes of FD were evaluated using the Rome questionnaire. The Gastrointestinal Symptom Rating Score, health-related quality of life (HR-QOL; SF-8), and psychological scores (HADS, STAI) were evaluated. The questionnaire was collected from a total of 205 patients, and 54.1% were FD patients. The ratio of FD patients under the Rome III criteria was 19% for epigastric pain syndrome (EPS), 38% for postprandial distress syndrome (PDS), and 43% for an overlap of EPS and PDS, but under the Rome IV criteria overlap decreased to 17% and PDS increased to 64%. Patients whose subtype changed from overlap under the Rome III criteria to PDS under the Rome IV criteria were compared with PDS patients whose subtype did not change between the Rome III and IV criteria. The comparison showed that the former had significantly lower early satiation rates and significantly higher acid reflux and abdominal pain scores, demonstrating that EPS symptoms due to acid reflux after meals were clearly present. As a result of changing from the Rome III criteria to the Rome IV criteria, the number of overlap patients decreased, and the number of PDS patients increased.
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spelling pubmed-91042962022-05-14 Epidemiology and Clinical Characteristics Based on the Rome III and IV Criteria of Japanese Patients with Functional Dyspepsia Aono, Sota Tomita, Toshihiko Tozawa, Katsuyuki Morishita, Daisuke Nakai, Keisuke Okugawa, Takuya Fukushima, Masashi Oshima, Tadayuki Fukui, Hirokazu Miwa, Hiroto J Clin Med Article The subtypes of functional dyspepsia (FD) differ depending on whether the Rome III criteria or the Rome IV criteria are used. We investigated the ability to diagnose FD patients using the Rome III and IV criteria. The subtypes of FD were evaluated using the Rome questionnaire. The Gastrointestinal Symptom Rating Score, health-related quality of life (HR-QOL; SF-8), and psychological scores (HADS, STAI) were evaluated. The questionnaire was collected from a total of 205 patients, and 54.1% were FD patients. The ratio of FD patients under the Rome III criteria was 19% for epigastric pain syndrome (EPS), 38% for postprandial distress syndrome (PDS), and 43% for an overlap of EPS and PDS, but under the Rome IV criteria overlap decreased to 17% and PDS increased to 64%. Patients whose subtype changed from overlap under the Rome III criteria to PDS under the Rome IV criteria were compared with PDS patients whose subtype did not change between the Rome III and IV criteria. The comparison showed that the former had significantly lower early satiation rates and significantly higher acid reflux and abdominal pain scores, demonstrating that EPS symptoms due to acid reflux after meals were clearly present. As a result of changing from the Rome III criteria to the Rome IV criteria, the number of overlap patients decreased, and the number of PDS patients increased. MDPI 2022-04-22 /pmc/articles/PMC9104296/ /pubmed/35566472 http://dx.doi.org/10.3390/jcm11092342 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Aono, Sota
Tomita, Toshihiko
Tozawa, Katsuyuki
Morishita, Daisuke
Nakai, Keisuke
Okugawa, Takuya
Fukushima, Masashi
Oshima, Tadayuki
Fukui, Hirokazu
Miwa, Hiroto
Epidemiology and Clinical Characteristics Based on the Rome III and IV Criteria of Japanese Patients with Functional Dyspepsia
title Epidemiology and Clinical Characteristics Based on the Rome III and IV Criteria of Japanese Patients with Functional Dyspepsia
title_full Epidemiology and Clinical Characteristics Based on the Rome III and IV Criteria of Japanese Patients with Functional Dyspepsia
title_fullStr Epidemiology and Clinical Characteristics Based on the Rome III and IV Criteria of Japanese Patients with Functional Dyspepsia
title_full_unstemmed Epidemiology and Clinical Characteristics Based on the Rome III and IV Criteria of Japanese Patients with Functional Dyspepsia
title_short Epidemiology and Clinical Characteristics Based on the Rome III and IV Criteria of Japanese Patients with Functional Dyspepsia
title_sort epidemiology and clinical characteristics based on the rome iii and iv criteria of japanese patients with functional dyspepsia
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9104296/
https://www.ncbi.nlm.nih.gov/pubmed/35566472
http://dx.doi.org/10.3390/jcm11092342
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