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Annoying Psoriasis and Atopic Dermatitis: A Narrative Review

Skin is an important organ that mainly functions as a barrier. Skin diseases can damage a person’s self-confidence and reduce their willingness to socialize, as well as their social behavior and willingness. When the skin appearance is abnormal, in addition to affecting the quality of life, it often...

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Autores principales: Chen, Wei-Yu, Chen, Shao-Chuan, Hsu, Shou-Yi, Lin, Yu-An, Shih, Chun-Ming, Huang, Chun-Yao, Wang, Kuo-Hsien, Lee, Ai-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9104570/
https://www.ncbi.nlm.nih.gov/pubmed/35563285
http://dx.doi.org/10.3390/ijms23094898
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author Chen, Wei-Yu
Chen, Shao-Chuan
Hsu, Shou-Yi
Lin, Yu-An
Shih, Chun-Ming
Huang, Chun-Yao
Wang, Kuo-Hsien
Lee, Ai-Wei
author_facet Chen, Wei-Yu
Chen, Shao-Chuan
Hsu, Shou-Yi
Lin, Yu-An
Shih, Chun-Ming
Huang, Chun-Yao
Wang, Kuo-Hsien
Lee, Ai-Wei
author_sort Chen, Wei-Yu
collection PubMed
description Skin is an important organ that mainly functions as a barrier. Skin diseases can damage a person’s self-confidence and reduce their willingness to socialize, as well as their social behavior and willingness. When the skin appearance is abnormal, in addition to affecting the quality of life, it often leads to personal, social, and psychological dysfunction and even induces depression. Psoriasis and atopic dermatitis are common chronic skin diseases. Their prevalence in the world is 3–10%, and there is an increasing trend year by year. These congenital or acquired factors cause the dysfunction of the immune system and then destroy the barrier function of the skin. Because these patients are flooded with a variety of inflammatory mediators, this causes skin cells to be in chronic inflammation. Therefore, psoriasis and atopic dermatitis are also considered systemic chronic inflammatory diseases. In the healthcare systems of developed countries, it is unavoidable to spend high costs to relieve symptoms of psoriasis and atopic dermatitis patients, because psoriasis and atopic dermatitis have a great influence on individuals and society. Giving a lot of attention and developing effective treatment methods are the topics that the medical community must work on together. Therefore, we used a narrative review manuscript to discuss pathogenesis, clinical classification, incidence, and treatment options, including topical medication, systemic therapeutics, immunosuppressive medication for psoriasis, and atopic dermatitis, as well as also comparing the differences between these two diseases. We look forward to providing readers with comprehensive information on psoriasis and atopic dermatitis through this review article.
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spelling pubmed-91045702022-05-14 Annoying Psoriasis and Atopic Dermatitis: A Narrative Review Chen, Wei-Yu Chen, Shao-Chuan Hsu, Shou-Yi Lin, Yu-An Shih, Chun-Ming Huang, Chun-Yao Wang, Kuo-Hsien Lee, Ai-Wei Int J Mol Sci Review Skin is an important organ that mainly functions as a barrier. Skin diseases can damage a person’s self-confidence and reduce their willingness to socialize, as well as their social behavior and willingness. When the skin appearance is abnormal, in addition to affecting the quality of life, it often leads to personal, social, and psychological dysfunction and even induces depression. Psoriasis and atopic dermatitis are common chronic skin diseases. Their prevalence in the world is 3–10%, and there is an increasing trend year by year. These congenital or acquired factors cause the dysfunction of the immune system and then destroy the barrier function of the skin. Because these patients are flooded with a variety of inflammatory mediators, this causes skin cells to be in chronic inflammation. Therefore, psoriasis and atopic dermatitis are also considered systemic chronic inflammatory diseases. In the healthcare systems of developed countries, it is unavoidable to spend high costs to relieve symptoms of psoriasis and atopic dermatitis patients, because psoriasis and atopic dermatitis have a great influence on individuals and society. Giving a lot of attention and developing effective treatment methods are the topics that the medical community must work on together. Therefore, we used a narrative review manuscript to discuss pathogenesis, clinical classification, incidence, and treatment options, including topical medication, systemic therapeutics, immunosuppressive medication for psoriasis, and atopic dermatitis, as well as also comparing the differences between these two diseases. We look forward to providing readers with comprehensive information on psoriasis and atopic dermatitis through this review article. MDPI 2022-04-28 /pmc/articles/PMC9104570/ /pubmed/35563285 http://dx.doi.org/10.3390/ijms23094898 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Chen, Wei-Yu
Chen, Shao-Chuan
Hsu, Shou-Yi
Lin, Yu-An
Shih, Chun-Ming
Huang, Chun-Yao
Wang, Kuo-Hsien
Lee, Ai-Wei
Annoying Psoriasis and Atopic Dermatitis: A Narrative Review
title Annoying Psoriasis and Atopic Dermatitis: A Narrative Review
title_full Annoying Psoriasis and Atopic Dermatitis: A Narrative Review
title_fullStr Annoying Psoriasis and Atopic Dermatitis: A Narrative Review
title_full_unstemmed Annoying Psoriasis and Atopic Dermatitis: A Narrative Review
title_short Annoying Psoriasis and Atopic Dermatitis: A Narrative Review
title_sort annoying psoriasis and atopic dermatitis: a narrative review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9104570/
https://www.ncbi.nlm.nih.gov/pubmed/35563285
http://dx.doi.org/10.3390/ijms23094898
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