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Prevalence of gestational diabetes and its association with stillbirth, preterm birth, macrosomia, abortion and cesarean delivery: a national prevalence study of 11 provinces in Iran
BACKGROUND: Gestational diabetes mellitus (GDM) is one of the most common metabolic disorders during pregnancy that significantly affects perinatal outcomes. OBJECTIVE: The aim of this study was to determine the prevalence of GDM and its relation with the incidence of stillbirth, preterm birth, macr...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Pacini Editore Srl
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9104678/ https://www.ncbi.nlm.nih.gov/pubmed/35603250 http://dx.doi.org/10.15167/2421-4248/jpmh2021.62.4.1788 |
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author | DARBANDI, MITRA REZAEIAN, SHAHAB DIANATINASAB, MOSTAFA YAGHOOBI, HALIME SOLTANI, MARYAM ETEMAD, KOOROSH VALADBEIGI, TANAZ TAHERPOUR, NILOUFAR HAJIPOUR, MAHMOUD SAEIDI, REZA |
author_facet | DARBANDI, MITRA REZAEIAN, SHAHAB DIANATINASAB, MOSTAFA YAGHOOBI, HALIME SOLTANI, MARYAM ETEMAD, KOOROSH VALADBEIGI, TANAZ TAHERPOUR, NILOUFAR HAJIPOUR, MAHMOUD SAEIDI, REZA |
author_sort | DARBANDI, MITRA |
collection | PubMed |
description | BACKGROUND: Gestational diabetes mellitus (GDM) is one of the most common metabolic disorders during pregnancy that significantly affects perinatal outcomes. OBJECTIVE: The aim of this study was to determine the prevalence of GDM and its relation with the incidence of stillbirth, preterm birth, macrosomia, abortion and cesarean section (C-section) delivery in pregnant women. METHODS: This cross-sectional study was conducted on 3675 pregnant women in 11 provinces across Iran. Cluster sampling was used to select samples from mothers covered by health plans in 11 provinces of Iran. Prevalence of adverse pregnancy outcomes, including preterm delivery, type of delivery, macrosomic preterm birth, miscarriage, stillbirth, infant death, and birth weight were measured, using family record and face-to-face interviews. Data were analyzed by logistic regression, using STATA14.2 software. RESULTS: About four percent of Iranian pregnant women had GDM during pregnancy. Prevalence of C-section was significantly higher in diabetic women than in the non-diabetic ones (53.19 vs 46.81, respectively, P < 0.001). Abortion in diabetic mothers was more than twice that of the non-diabetic mothers (P < 0.001). In the adjusted logistic regression model, the odds of stillbirth in mothers with GDM were 1.8 (95% CI: 1.11, 2.91, P = 0.018) times higher than that of the non-diabetics. The odds of macrosomia in diabetic women was about 7 times higher than the non-diabetic women (95% CI: 2.81, 17.14, P < 0.001). The odds of GDM had an increasing trend according to the BMI (p < 0.001). The risk of GDM were significantly lower, according to the daily physical activity (PA) (p < 0.001). CONCLUSION: The GDM prevalence has a decreasing trend in Iran. It increases the adverse pregnancy outcomes such as stillbirth, neonatal deaths, macrosomia, preterm birth, abortion and C-section delivery. As, some of these consequences like macrosomia are not treatable, thus early prevention is very crucial. |
format | Online Article Text |
id | pubmed-9104678 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Pacini Editore Srl |
record_format | MEDLINE/PubMed |
spelling | pubmed-91046782022-05-19 Prevalence of gestational diabetes and its association with stillbirth, preterm birth, macrosomia, abortion and cesarean delivery: a national prevalence study of 11 provinces in Iran DARBANDI, MITRA REZAEIAN, SHAHAB DIANATINASAB, MOSTAFA YAGHOOBI, HALIME SOLTANI, MARYAM ETEMAD, KOOROSH VALADBEIGI, TANAZ TAHERPOUR, NILOUFAR HAJIPOUR, MAHMOUD SAEIDI, REZA J Prev Med Hyg Health Promotion BACKGROUND: Gestational diabetes mellitus (GDM) is one of the most common metabolic disorders during pregnancy that significantly affects perinatal outcomes. OBJECTIVE: The aim of this study was to determine the prevalence of GDM and its relation with the incidence of stillbirth, preterm birth, macrosomia, abortion and cesarean section (C-section) delivery in pregnant women. METHODS: This cross-sectional study was conducted on 3675 pregnant women in 11 provinces across Iran. Cluster sampling was used to select samples from mothers covered by health plans in 11 provinces of Iran. Prevalence of adverse pregnancy outcomes, including preterm delivery, type of delivery, macrosomic preterm birth, miscarriage, stillbirth, infant death, and birth weight were measured, using family record and face-to-face interviews. Data were analyzed by logistic regression, using STATA14.2 software. RESULTS: About four percent of Iranian pregnant women had GDM during pregnancy. Prevalence of C-section was significantly higher in diabetic women than in the non-diabetic ones (53.19 vs 46.81, respectively, P < 0.001). Abortion in diabetic mothers was more than twice that of the non-diabetic mothers (P < 0.001). In the adjusted logistic regression model, the odds of stillbirth in mothers with GDM were 1.8 (95% CI: 1.11, 2.91, P = 0.018) times higher than that of the non-diabetics. The odds of macrosomia in diabetic women was about 7 times higher than the non-diabetic women (95% CI: 2.81, 17.14, P < 0.001). The odds of GDM had an increasing trend according to the BMI (p < 0.001). The risk of GDM were significantly lower, according to the daily physical activity (PA) (p < 0.001). CONCLUSION: The GDM prevalence has a decreasing trend in Iran. It increases the adverse pregnancy outcomes such as stillbirth, neonatal deaths, macrosomia, preterm birth, abortion and C-section delivery. As, some of these consequences like macrosomia are not treatable, thus early prevention is very crucial. Pacini Editore Srl 2022-01-31 /pmc/articles/PMC9104678/ /pubmed/35603250 http://dx.doi.org/10.15167/2421-4248/jpmh2021.62.4.1788 Text en ©2021 Pacini Editore SRL, Pisa, Italy https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed in accordance with the CC-BY-NC-ND (Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International) license. The article can be used by giving appropriate credit and mentioning the license, but only for non-commercial purposes and only in the original version. For further information: https://creativecommons.org/licenses/by-nc-nd/4.0/deed.en |
spellingShingle | Health Promotion DARBANDI, MITRA REZAEIAN, SHAHAB DIANATINASAB, MOSTAFA YAGHOOBI, HALIME SOLTANI, MARYAM ETEMAD, KOOROSH VALADBEIGI, TANAZ TAHERPOUR, NILOUFAR HAJIPOUR, MAHMOUD SAEIDI, REZA Prevalence of gestational diabetes and its association with stillbirth, preterm birth, macrosomia, abortion and cesarean delivery: a national prevalence study of 11 provinces in Iran |
title | Prevalence of gestational diabetes and its association with stillbirth, preterm birth, macrosomia, abortion and cesarean delivery: a national prevalence study of 11 provinces in Iran |
title_full | Prevalence of gestational diabetes and its association with stillbirth, preterm birth, macrosomia, abortion and cesarean delivery: a national prevalence study of 11 provinces in Iran |
title_fullStr | Prevalence of gestational diabetes and its association with stillbirth, preterm birth, macrosomia, abortion and cesarean delivery: a national prevalence study of 11 provinces in Iran |
title_full_unstemmed | Prevalence of gestational diabetes and its association with stillbirth, preterm birth, macrosomia, abortion and cesarean delivery: a national prevalence study of 11 provinces in Iran |
title_short | Prevalence of gestational diabetes and its association with stillbirth, preterm birth, macrosomia, abortion and cesarean delivery: a national prevalence study of 11 provinces in Iran |
title_sort | prevalence of gestational diabetes and its association with stillbirth, preterm birth, macrosomia, abortion and cesarean delivery: a national prevalence study of 11 provinces in iran |
topic | Health Promotion |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9104678/ https://www.ncbi.nlm.nih.gov/pubmed/35603250 http://dx.doi.org/10.15167/2421-4248/jpmh2021.62.4.1788 |
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