Genome-wide transcript and protein analysis highlights the role of protein homeostasis in the aging mouse heart

Investigation of the molecular mechanisms of aging in the human heart is challenging because of confounding factors, such as diet and medications, as well as limited access to tissues from healthy aging individuals. The laboratory mouse provides an ideal model to study aging in healthy individuals i...

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Detalles Bibliográficos
Autores principales: Gerdes Gyuricza, Isabela, Chick, Joel M., Keele, Gregory R., Deighan, Andrew G., Munger, Steven C., Korstanje, Ron, Gygi, Steven P., Churchill, Gary A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9104701/
https://www.ncbi.nlm.nih.gov/pubmed/35277432
http://dx.doi.org/10.1101/gr.275672.121

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