Hemin-Induced Endothelial Dysfunction and Endothelial to Mesenchymal Transition in the Pathogenesis of Pulmonary Hypertension Due to Chronic Hemolysis

Pulmonary hypertension in sickle cell disease is an independent predictor of mortality, yet the pathogenesis of pulmonary vascular disease in chronic hemolytic disorders remains incompletely understood and treatment options are limited primarily to supportive care. The release of extracellular hemog...

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Detalles Bibliográficos
Autores principales: Gonzales, Janae, Holbert, Kelsey, Czysz, Kamryn, George, Joseph, Fernandes, Caroline, Fraidenburg, Dustin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9104708/
https://www.ncbi.nlm.nih.gov/pubmed/35563154
http://dx.doi.org/10.3390/ijms23094763

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