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The PDE4 Inhibitor Tanimilast Restrains the Tissue-Damaging Properties of Human Neutrophils
Neutrophils, the most abundant subset of leukocytes in the blood, play a pivotal role in host response against invading pathogens. However, in respiratory diseases, excessive infiltration and activation of neutrophils can lead to tissue damage. Tanimilast-international non-proprietary name of CHF600...
Autores principales: | Schioppa, Tiziana, Nguyen, Hoang Oanh, Salvi, Valentina, Maugeri, Norma, Facchinetti, Fabrizio, Villetti, Gino, Civelli, Maurizio, Gaudenzi, Carolina, Passari, Mauro, Sozio, Francesca, Barbazza, Ilaria, Tamassia, Nicola, Cassatella, Marco A., Del Prete, Annalisa, Bosisio, Daniela, Tiberio, Laura |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9104715/ https://www.ncbi.nlm.nih.gov/pubmed/35563373 http://dx.doi.org/10.3390/ijms23094982 |
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