The Genetic and Molecular Analyses of RAD51C and RAD51D Identifies Rare Variants Implicated in Hereditary Ovarian Cancer from a Genetically Unique Population

SIMPLE SUMMARY: We have investigated RAD51C and RAD51D, hereditary ovarian cancer risk genes, in French Canadians of Quebec, Canada. This population of Western European origins exhibits a unique genetic landscape as shown by the frequency of carriers of specific rare pathogenic variants. As studying...

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Detalles Bibliográficos
Autores principales: Alenezi, Wejdan M., Milano, Larissa, Fierheller, Caitlin T., Serruya, Corinne, Revil, Timothée, Oros, Kathleen K., Behl, Supriya, Arcand, Suzanna L., Nayar, Porangana, Spiegelman, Dan, Gravel, Simon, Mes-Masson, Anne-Marie, Provencher, Diane, Foulkes, William D., El Haffaf, Zaki, Rouleau, Guy, Bouchard, Luigi, Greenwood, Celia M. T., Masson, Jean-Yves, Ragoussis, Jiannis, Tonin, Patricia N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9104874/
https://www.ncbi.nlm.nih.gov/pubmed/35565380
http://dx.doi.org/10.3390/cancers14092251

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