Spiro-Oxindole Skeleton Compounds Are Efficient Inhibitors for Indoleamine 2,3-Dioxygenase 1: An Attractive Target for Tumor Immunotherapy

Indoleamine 2,3-dioxygenase 1 (IDO1) is an attractive heme enzyme for its significant function in cancer immunotherapy. Potent IDO1 inhibitors have been discovered for decades, whereas no clinical drugs are used for cancer treatment up to now. With the goal of developing medically valuable IDO inhib...

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Detalles Bibliográficos
Autores principales: Yan, Daojing, Xu, Jiakun, Wang, Xiang, Zhang, Jiaxing, Zhao, Gang, Lin, Yingwu, Tan, Xiangshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9104902/
https://www.ncbi.nlm.nih.gov/pubmed/35563059
http://dx.doi.org/10.3390/ijms23094668

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