Cargando…
Proliferation and Invasion of Melanoma Are Suppressed by a Plant Protease Inhibitor, Leading to Downregulation of Survival/Death-Related Proteins
Cell adhesion and migration are crucial for cancer progression and malignancy. Drugs available for the treatment of metastatic melanoma are expensive and unfit for certain patients. Therefore, there is still a need to identify new drugs that block tumor cell development. We investigated the effects...
Autores principales: | Bonturi, Camila Ramalho, Salu, Bruno Ramos, Bonazza, Camila Nimri, Sinigaglia, Rita de Cassia, Rodrigues, Tiago, Alvarez-Flores, Miryam Paola, Chudzinski-Tavassi, Ana Marisa, Oliva, Maria Luiza Vilela |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9104945/ https://www.ncbi.nlm.nih.gov/pubmed/35566311 http://dx.doi.org/10.3390/molecules27092956 |
Ejemplares similares
-
A snake venom-analog peptide that inhibits SARS-CoV-2 and papain-like protease displays antithrombotic activity in mice arterial thrombosis model, without interfering with bleeding time
por: Nogueira, Ruben Siedlarczyk, et al.
Publicado: (2023) -
Modulation of STAT-1, STAT-3, and STAT-6 activities in THP-1 derived macrophages infected with two Trypanosoma cruzi strains
por: Oliveira, Melissa Martins, et al.
Publicado: (2022) -
Impairment of SK-MEL-28 Development—A Human Melanoma Cell Line—By the Crataeva tapia Bark Lectin and Its Sequence-Derived Peptides
por: Lie, Kathleen Chwen Ming, et al.
Publicado: (2023) -
Differences in the Inhibitory Specificity Distinguish the Efficacy of Plant Protease Inhibitors on Mouse Fibrosarcoma
por: Yoo Im, Sonia, et al.
Publicado: (2021) -
Plant Kunitz Inhibitors and Their Interaction with Proteases: Current and Potential Pharmacological Targets
por: Bonturi, Camila Ramalho, et al.
Publicado: (2022)