Synthesis and In-Vivo Evaluation of Benzoxazole Derivatives as Promising Anti-Psoriatic Drugs for Clinical Use

2-(4-Chlorophenyl)-5-benzoxazoleacetic acid (CBA) and its ester, methyl-2-(4-chloro-phenyl)-5-benzoxazoleacetate (MCBA), were synthesized, and their structures were confirmed by (1)HNMR, IR, and mass spectrophotometry. The anti-psoriatic activities of CBA and MCBA were tested using an imiquimod (IMQ...

Descripción completa

Detalles Bibliográficos
Autores principales: Ayoub, Rami, Jilani, Jamal, Jarrar, Qais, Alani, Raad, Ardianto, Chrismawan, Goh, Khang Wen, Ali, Dalia, Moshawih, Said
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9104975/
https://www.ncbi.nlm.nih.gov/pubmed/35566373
http://dx.doi.org/10.3390/molecules27093023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9104975/
https://www.ncbi.nlm.nih.gov/pubmed/35566373
http://dx.doi.org/10.3390/molecules27093023

Ejemplares similares