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Synthesis and In-Vivo Evaluation of Benzoxazole Derivatives as Promising Anti-Psoriatic Drugs for Clinical Use
2-(4-Chlorophenyl)-5-benzoxazoleacetic acid (CBA) and its ester, methyl-2-(4-chloro-phenyl)-5-benzoxazoleacetate (MCBA), were synthesized, and their structures were confirmed by (1)HNMR, IR, and mass spectrophotometry. The anti-psoriatic activities of CBA and MCBA were tested using an imiquimod (IMQ...
Autores principales: | Ayoub, Rami, Jilani, Jamal, Jarrar, Qais, Alani, Raad, Ardianto, Chrismawan, Goh, Khang Wen, Ali, Dalia, Moshawih, Said |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9104975/ https://www.ncbi.nlm.nih.gov/pubmed/35566373 http://dx.doi.org/10.3390/molecules27093023 |
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