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Pravastatin Administration Alleviates Kanamycin-Induced Cochlear Injury and Hearing Loss

The effect of statins on aminoglycoside-induced ototoxicity is controversial. This study aimed to explore the role of pravastatin (PV) in kanamycin-induced hearing loss in rats. Adult rats were intraperitoneally treated with 20 mg/kg/day of kanamycin (KM) for 10 days. In the PV- and PV + KM-treated...

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Detalles Bibliográficos
Autores principales: Lee, Chang Ho, Jeon, Jiwon, Lee, So Min, Kim, So Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9105065/
https://www.ncbi.nlm.nih.gov/pubmed/35562915
http://dx.doi.org/10.3390/ijms23094524