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Surface Hydration Protects Cystic Fibrosis Airways from Infection by Restoring Junctional Networks

Defective hydration of airway surface mucosa is associated with recurrent lung infection in cystic fibrosis (CF), a disease caused by CF transmembrane conductance regulator (CFTR) gene mutations. Whether the composition and/or presence of an airway surface liquid (ASL) is sufficient to prevent infec...

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Detalles Bibliográficos
Autores principales: Simonin, Juliette L., Luscher, Alexandre, Losa, Davide, Badaoui, Mehdi, van Delden, Christian, Köhler, Thilo, Chanson, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9105190/
https://www.ncbi.nlm.nih.gov/pubmed/35563895
http://dx.doi.org/10.3390/cells11091587