Cargando…

Surface Hydration Protects Cystic Fibrosis Airways from Infection by Restoring Junctional Networks

Defective hydration of airway surface mucosa is associated with recurrent lung infection in cystic fibrosis (CF), a disease caused by CF transmembrane conductance regulator (CFTR) gene mutations. Whether the composition and/or presence of an airway surface liquid (ASL) is sufficient to prevent infec...

Descripción completa

Detalles Bibliográficos
Autores principales:	Simonin, Juliette L., Luscher, Alexandre, Losa, Davide, Badaoui, Mehdi, van Delden, Christian, Köhler, Thilo, Chanson, Marc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9105190/ https://www.ncbi.nlm.nih.gov/pubmed/35563895 http://dx.doi.org/10.3390/cells11091587

Ejemplares similares

Targeting HuR-Vav3 mRNA interaction prevents Pseudomonas aeruginosa adhesion to the cystic fibrosis airway epithelium
por: Badaoui, Mehdi, et al.
Publicado: (2023)

Modulation of Ion Transport to Restore Airway Hydration in Cystic Fibrosis
por: Reihill, James A., et al.
Publicado: (2021)

Combined Bacteriophage and Antibiotic Treatment Prevents Pseudomonas aeruginosa Infection of Wild Type and cftr- Epithelial Cells
por: Luscher, Alexandre, et al.
Publicado: (2020)

Intercellular Communication in Airway Epithelial Cell Regeneration: Potential Roles of Connexins and Pannexins
por: Badaoui, Mehdi, et al.
Publicado: (2023)

Airway surface liquid acidification initiates host defense abnormalities in Cystic Fibrosis
por: Simonin, Juliette, et al.
Publicado: (2019)

Transcriptomic profile of cystic fibrosis airway epithelial cells undergoing repair
por: Zoso, Alice, et al.
Publicado: (2019)

Transcriptional profiling of Pseudomonas aeruginosa and Staphylococcus aureus during in vitro co-culture
por: Tognon, Mikaël, et al.
Publicado: (2019)

Author Correction: Airway surface liquid acidification initiates host defense abnormalities in Cystic Fibrosis
por: Simonin, Juliette, et al.
Publicado: (2019)

Personalized aerosolised bacteriophage treatment of a chronic lung infection due to multidrug-resistant Pseudomonas aeruginosa
por: Köhler, Thilo, et al.
Publicado: (2023)

Author Correction: Personalized aerosolised bacteriophage treatment of a chronic lung infection due to multidrug-resistant Pseudomonas aeruginosa
por: Köhler, Thilo, et al.
Publicado: (2023)

TMEM16A: An Alternative Approach to Restoring Airway Anion Secretion in Cystic Fibrosis?
por: Danahay, Henry, et al.
Publicado: (2020)

Strategies to circumvent the CFTR defect in cystic fibrosis
por: Becq, Frédéric, et al.
Publicado: (2013)

The fungal airway microbiome in cystic fibrosis and non-cystic fibrosis bronchiectasis
por: Cuthbertson, Leah, et al.
Publicado: (2021)

Airway inflammatory markers in individuals with cystic fibrosis and non-cystic fibrosis bronchiectasis
por: Bergin, David A, et al.
Publicado: (2013)

Airway Surface Liquid and Impaired Antiviral Defense in Cystic Fibrosis
por: Voynow, Judith A., et al.
Publicado: (2020)

CFTR Delivery to 25% of Surface Epithelial Cells Restores Normal Rates of Mucus Transport to Human Cystic Fibrosis Airway Epithelium
por: Zhang, Liqun, et al.
Publicado: (2009)

Characterization of two rat models of cystic fibrosis—KO and F508del CFTR—Generated by Crispr‐Cas9
por: Dreano, Elise, et al.
Publicado: (2019)

New Developments in Cystic Fibrosis Airway Inflammation
por: Palaniyar, Nades, et al.
Publicado: (2015)

The cystic fibrosis lower airways microbial metagenome
por: Moran Losada, Patricia, et al.
Publicado: (2016)

Airway Epithelium Dysfunction in Cystic Fibrosis and COPD
por: De Rose, Virginia, et al.
Publicado: (2018)

The Cystic Fibrosis Upper and Lower Airway Metagenome
por: Pienkowska, Katarzyna, et al.
Publicado: (2023)

Airway surface liquid pH is not acidic in children with cystic fibrosis
por: Schultz, André, et al.
Publicado: (2017)

Physiological levels of lipoxin A(4) inhibit ENaC and restore airway surface liquid height in cystic fibrosis bronchial epithelium
por: Al‐Alawi, Mazen, et al.
Publicado: (2014)

Adaptive and Mutational Responses to Peptide Dendrimer Antimicrobials in Pseudomonas aeruginosa
por: Ben Jeddou, Fatma, et al.
Publicado: (2020)

Modulator Combination Improves In Vitro the Microrheological Properties of the Airway Surface Liquid of Cystic Fibrosis Airway Epithelia
por: Ludovico, Alessandra, et al.
Publicado: (2022)

Assessment of p.Phe508del-CFTR functional restoration in pediatric primary cystic fibrosis airway epithelial cells
por: Sutanto, Erika N., et al.
Publicado: (2018)

Abnormal localization of cystic fibrosis transmembrane conductance regulator in primary cultures of cystic fibrosis airway epithelia
Publicado: (1992)

Proteome of airway surface liquid and mucus in newborn wildtype and cystic fibrosis piglets
por: Rodriguez-Piñeiro, Ana M., et al.
Publicado: (2023)

Inflammation as a Regulator of the Airway Surface Liquid pH in Cystic Fibrosis
por: Rehman, Tayyab, et al.
Publicado: (2023)

Klotho Inhibits Interleukin-8 Secretion from Cystic Fibrosis Airway Epithelia
por: Krick, Stefanie, et al.
Publicado: (2017)

L-Ornithine Derived Polyamines in Cystic Fibrosis Airways
por: Grasemann, Hartmut, et al.
Publicado: (2012)

MicroRNA Expression in Cystic Fibrosis Airway Epithelium
por: Greene, Catherine M.
Publicado: (2013)

Airway disease phenotypes in animal models of cystic fibrosis
por: McCarron, Alexandra, et al.
Publicado: (2018)

The Involvement of Glycosaminoglycans in Airway Disease Associated with Cystic Fibrosis
por: Reeves, Emer P., et al.
Publicado: (2011)

Airway Inflammatory/Immune Responses in COPD and Cystic Fibrosis
por: De Rose, Virginia, et al.
Publicado: (2018)

Longitudinal development of the airway microbiota in infants with cystic fibrosis
por: Ahmed, Bushra, et al.
Publicado: (2019)

The metabolic footprint of the airway bacterial community in cystic fibrosis
por: Narayanamurthy, Vaishnavi, et al.
Publicado: (2017)

Shifting Landscape of Airway Infection in Early Cystic Fibrosis
por: Hoppe, Jordana E., et al.
Publicado: (2019)

Approaches to Targeting Bacterial Biofilms in Cystic Fibrosis Airways
por: Martin, Isaac, et al.
Publicado: (2021)

Ecological Succession of Polymicrobial Communities in the Cystic Fibrosis Airways
por: Khanolkar, Rutvij A., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_lro5r6o9bc9jp0i5nu08etm922