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Humanised Mice and Immunodeficient Mice (NSG) Are Equally Sensitive for Prediction of Stem Cell Malignancy in the Teratoma Assay

The use of human pluripotent stem cells (hPSCs) in regenerative medicine has great potential. However, it is important to exclude that these cells can undergo malignant transformation, which could lead to the development of malignant tumours. This property of hPSCs is currently being tested using th...

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Detalles Bibliográficos
Autores principales: Bialecka, Monika, Montilla-Rojo, Joaquin, Roelen, Bernard A. J., Gillis, Ad J., Looijenga, Leendert H. J., Salvatori, Daniela. C. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9105268/
https://www.ncbi.nlm.nih.gov/pubmed/35563071
http://dx.doi.org/10.3390/ijms23094680