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Preparation of Duplex Sequencing Libraries for Archival Paraffin-Embedded Tissue Samples Using Single-Strand-Specific Nuclease P1

DNA from formalin-fixed paraffin-embedded (FFPE) tissues, which are frequently utilized in cancer research, is significantly affected by chemical degradation. It was suggested that approaches that are based on duplex sequencing can significantly improve the accuracy of mutation detection in FFPE-der...

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Detalles Bibliográficos
Autores principales:	Mitiushkina, Natalia V., Yanus, Grigory A., Kuligina, Ekatherina Sh., Laidus, Tatiana A., Romanko, Alexandr A., Kholmatov, Maksim M., Ivantsov, Alexandr O., Aleksakhina, Svetlana N., Imyanitov, Evgeny N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9105346/ https://www.ncbi.nlm.nih.gov/pubmed/35562977 http://dx.doi.org/10.3390/ijms23094586

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