Rotenone-Induced 4-HNE Aggresome Formation and Degradation in HL-1 Cardiomyocytes: Role of Autophagy Flux

Reactive oxygen species (ROS) cause oxidative stress by generating reactive aldehydes known as 4-hydroxynonenal (4-HNE). 4-HNE modifies protein via covalent adduction; however, little is known about the degradation mechanism of 4-HNE-adducted proteins. Autophagy is a dynamic process that maintains c...

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Detalles Bibliográficos
Autores principales: Sharma, Sudha, Patel, Foram, Ara, Hosne, Bess, Ezra, Shum, Alika, Bhattarai, Susmita, Subedi, Utsab, Bell, Daquonte Sanard, Bhuiyan, Md. Shenuarin, Sun, Hong, Batinic-Haberle, Ines, Panchatcharam, Manikandan, Miriyala, Sumitra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9105393/
https://www.ncbi.nlm.nih.gov/pubmed/35563066
http://dx.doi.org/10.3390/ijms23094675

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