Escherichia coli tRNA 2-Selenouridine Synthase (SelU): Elucidation of Substrate Specificity to Understand the Role of S-Geranyl-tRNA in the Conversion of 2-Thio- into 2-Selenouridines in Bacterial tRNA

The bacterial enzyme tRNA 2-selenouridine synthase (SelU) is responsible for the conversion of 5-substituted 2-thiouridine (R5S2U), present in the anticodon of some bacterial tRNAs, into 5-substituted 2-selenouridine (R5Se2U). We have already demonstrated using synthetic RNAs that transformation S2U...

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Detalles Bibliográficos
Autores principales: Szczupak, Patrycja, Sierant, Malgorzata, Wielgus, Ewelina, Radzikowska-Cieciura, Ewa, Kulik, Katarzyna, Krakowiak, Agnieszka, Kuwerska, Paulina, Leszczynska, Grazyna, Nawrot, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9105526/
https://www.ncbi.nlm.nih.gov/pubmed/35563829
http://dx.doi.org/10.3390/cells11091522

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