Cerebral Cavernous Malformation Pathogenesis: Investigating Lesion Formation and Progression with Animal Models

Cerebral cavernous malformation (CCM) is a cerebromicrovascular disease that affects up to 0.5% of the population. Vessel dilation, decreased endothelial cell–cell contact, and loss of junctional complexes lead to loss of brain endothelial barrier integrity and hemorrhagic lesion formation. Leakage...

Descripción completa

Detalles Bibliográficos
Autores principales: Phillips, Chelsea M., Stamatovic, Svetlana M., Keep, Richard F., Andjelkovic, Anuska V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9105545/
https://www.ncbi.nlm.nih.gov/pubmed/35563390
http://dx.doi.org/10.3390/ijms23095000

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9105545/
https://www.ncbi.nlm.nih.gov/pubmed/35563390
http://dx.doi.org/10.3390/ijms23095000

Ejemplares similares