Cerebral Cavernous Malformation Pathogenesis: Investigating Lesion Formation and Progression with Animal Models

Cerebral cavernous malformation (CCM) is a cerebromicrovascular disease that affects up to 0.5% of the population. Vessel dilation, decreased endothelial cell–cell contact, and loss of junctional complexes lead to loss of brain endothelial barrier integrity and hemorrhagic lesion formation. Leakage...

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Detalles Bibliográficos
Autores principales: Phillips, Chelsea M., Stamatovic, Svetlana M., Keep, Richard F., Andjelkovic, Anuska V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9105545/
https://www.ncbi.nlm.nih.gov/pubmed/35563390
http://dx.doi.org/10.3390/ijms23095000

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