Synthesis of Four Enantiomers of (1-Amino-3-Hydroxypropane-1,3-Diyl)Diphosphonic Acid as Diphosphonate Analogues of 4-Hydroxyglutamic Acid

All the enantiomers of (1-amino-3-hydroxypropane-1,3-diyl)diphosphonic acid, newly design phosphonate analogues of 4-hydroxyglutamic acids, were obtained. The synthetic strategy involved Abramov reactions of diethyl (R)- and (S)-1-(N-Boc-amino)-3-oxopropylphosphonates with diethyl phosphite, separat...

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Detalles Bibliográficos
Autores principales: Lebelt, Liwia, Głowacka, Iwona E., Piotrowska, Dorota G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9105571/
https://www.ncbi.nlm.nih.gov/pubmed/35566049
http://dx.doi.org/10.3390/molecules27092699

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9105571/
https://www.ncbi.nlm.nih.gov/pubmed/35566049
http://dx.doi.org/10.3390/molecules27092699

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