Cargando…

Consumption of Vegetables Is Associated with Systemic Inflammation in Older Adults

It is hypothesized that healthy diets rich in fruits and vegetables (FV) can modulate the inflammatory status in older adults. However, to determine the actual impact of FV on inflammatory status, adiposity level and objectively assessed physical activity (PA) behaviors need to be considered. The ai...

Descripción completa

Detalles Bibliográficos
Autores principales: Papaioannou, Konstantinos-Georgios, Kadi, Fawzi, Nilsson, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9105870/
https://www.ncbi.nlm.nih.gov/pubmed/35565733
http://dx.doi.org/10.3390/nu14091765
_version_ 1784708143045935104
author Papaioannou, Konstantinos-Georgios
Kadi, Fawzi
Nilsson, Andreas
author_facet Papaioannou, Konstantinos-Georgios
Kadi, Fawzi
Nilsson, Andreas
author_sort Papaioannou, Konstantinos-Georgios
collection PubMed
description It is hypothesized that healthy diets rich in fruits and vegetables (FV) can modulate the inflammatory status in older adults. However, to determine the actual impact of FV on inflammatory status, adiposity level and objectively assessed physical activity (PA) behaviors need to be considered. The aim of the present study was to explore associations between FV intake and biomarkers of systemic inflammation in older adults. Based on a sample of 233 older adults (65–70 years old), the following inflammatory biomarkers were assessed: C-reactive protein (CRP), fibrinogen, interleukin-6 (IL-6), IL-10, IL-18, and monocyte chemoattractant protein-1 (MCP-1). FV intake was assessed by self-report, and PA behaviors encompassing time spent sedentary and in moderate-to-vigorous PA (MVPA) were determined using accelerometers. Associations between FV intake and inflammatory biomarkers were analyzed using stepwise linear regression models while adjusting for several covariates, including health-related food groups, adherence to the MVPA guidelines, total sedentary time, and waist circumference. While no significant associations were observed for the total FV intake, the vegetable intake was inversely associated with levels of IL6 (β = −0.15; p < 0.05). In contrast, fruit intake was not associated with any inflammatory biomarker. In conclusion, our findings indicate beneficial associations between vegetable intake and levels of a pro-inflammatory biomarker in older adults, which strengthens public health efforts to promote vegetable-rich diets in older adults to mitigate age-related systemic inflammation.
format Online
Article
Text
id pubmed-9105870
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-91058702022-05-14 Consumption of Vegetables Is Associated with Systemic Inflammation in Older Adults Papaioannou, Konstantinos-Georgios Kadi, Fawzi Nilsson, Andreas Nutrients Article It is hypothesized that healthy diets rich in fruits and vegetables (FV) can modulate the inflammatory status in older adults. However, to determine the actual impact of FV on inflammatory status, adiposity level and objectively assessed physical activity (PA) behaviors need to be considered. The aim of the present study was to explore associations between FV intake and biomarkers of systemic inflammation in older adults. Based on a sample of 233 older adults (65–70 years old), the following inflammatory biomarkers were assessed: C-reactive protein (CRP), fibrinogen, interleukin-6 (IL-6), IL-10, IL-18, and monocyte chemoattractant protein-1 (MCP-1). FV intake was assessed by self-report, and PA behaviors encompassing time spent sedentary and in moderate-to-vigorous PA (MVPA) were determined using accelerometers. Associations between FV intake and inflammatory biomarkers were analyzed using stepwise linear regression models while adjusting for several covariates, including health-related food groups, adherence to the MVPA guidelines, total sedentary time, and waist circumference. While no significant associations were observed for the total FV intake, the vegetable intake was inversely associated with levels of IL6 (β = −0.15; p < 0.05). In contrast, fruit intake was not associated with any inflammatory biomarker. In conclusion, our findings indicate beneficial associations between vegetable intake and levels of a pro-inflammatory biomarker in older adults, which strengthens public health efforts to promote vegetable-rich diets in older adults to mitigate age-related systemic inflammation. MDPI 2022-04-23 /pmc/articles/PMC9105870/ /pubmed/35565733 http://dx.doi.org/10.3390/nu14091765 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Papaioannou, Konstantinos-Georgios
Kadi, Fawzi
Nilsson, Andreas
Consumption of Vegetables Is Associated with Systemic Inflammation in Older Adults
title Consumption of Vegetables Is Associated with Systemic Inflammation in Older Adults
title_full Consumption of Vegetables Is Associated with Systemic Inflammation in Older Adults
title_fullStr Consumption of Vegetables Is Associated with Systemic Inflammation in Older Adults
title_full_unstemmed Consumption of Vegetables Is Associated with Systemic Inflammation in Older Adults
title_short Consumption of Vegetables Is Associated with Systemic Inflammation in Older Adults
title_sort consumption of vegetables is associated with systemic inflammation in older adults
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9105870/
https://www.ncbi.nlm.nih.gov/pubmed/35565733
http://dx.doi.org/10.3390/nu14091765
work_keys_str_mv AT papaioannoukonstantinosgeorgios consumptionofvegetablesisassociatedwithsystemicinflammationinolderadults
AT kadifawzi consumptionofvegetablesisassociatedwithsystemicinflammationinolderadults
AT nilssonandreas consumptionofvegetablesisassociatedwithsystemicinflammationinolderadults