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Acute T-Cell-Driven Inflammation Requires the Endoglycosidase Heparanase-1 from Multiple Cell Types

It has been accepted for decades that T lymphocytes and metastasising tumour cells traverse basement membranes (BM) by deploying a battery of degradative enzymes, particularly proteases. However, since many redundant proteases can solubilise BM it has been difficult to prove that proteases aid cell...

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Detalles Bibliográficos
Autores principales: Wu, Zuopeng, Sweet, Rebecca A., Hoyne, Gerard F., Simeonovic, Charmaine J., Parish, Christopher R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9105945/
https://www.ncbi.nlm.nih.gov/pubmed/35563015
http://dx.doi.org/10.3390/ijms23094625