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ST2825, a Small Molecule Inhibitor of MyD88, Suppresses NF-κB Activation and the ROS/NLRP3/Cleaved Caspase-1 Signaling Pathway to Attenuate Lipopolysaccharide-Stimulated Neuroinflammation

Neuroinflammation characterized by microglia activation is the mechanism of the occurrence and development of various central nervous system diseases. ST2825, as a peptide-mimetic MyD88 homodimerization inhibitor, has been identified as crucial molecule with an anti-inflammatory role in several immu...

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Detalles Bibliográficos
Autores principales:	Zhang, Shan-Shan, Liu, Man, Liu, Dong-Ni, Shang, Yu-Fu, Wang, Yue-Hua, Du, Guan-Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106063/ https://www.ncbi.nlm.nih.gov/pubmed/35566338 http://dx.doi.org/10.3390/molecules27092990

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