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MicroRNA 322-5p reduced neuronal inflammation via the TLR4/TRAF6/NF-κB axis in a rat epilepsy model

This study aimed to determine whether microRNA-322-5p regulates seizure and seizure damage by targeting the TLR4/TRAF6/NF-κB-associated inflammatory signaling pathway. In a pilocarpine-induced epileptic rat model, the expressions of miR-322-5p, TLR4, NF-κB, TRAF6, IRF5, IL-1β, and GABA were assessed...

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Detalles Bibliográficos
Autores principales: Zhou, Qin, Wang, Qiong, He, Baomei, Kong, Haibo, Luo, Huanjun, Wang, Xiaowei, Wang, Wenlan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106113/
https://www.ncbi.nlm.nih.gov/pubmed/35647304
http://dx.doi.org/10.1515/med-2022-0485