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KDM3A Inhibition Ameliorates Hyperglycemia-Mediated Myocardial Injury by Epigenetic Modulation of Nuclear Factor Kappa-B/P65

OBJECTIVES: Even after the glucose level returns to normal, hyperglycemia-induced cardiac dysfunction as well as reactive oxygen species (ROS) generation, inflammatory responses, and apoptosis continued deterioration, showing a long-lasting adverse effect on cardiac function and structure. We aimed...

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Detalles Bibliográficos
Autores principales:	Zhang, Bofang, Zhang, Jing, Liu, Gen, Guo, Xin, Liu, Xiaopei, Chen, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cardiovascular Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106140/ https://www.ncbi.nlm.nih.gov/pubmed/35571189 http://dx.doi.org/10.3389/fcvm.2022.870999

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