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Recombination affects allele-specific expression of deleterious variants in human populations

How the genetic composition of a population changes through stochastic processes, such as genetic drift, in combination with deterministic processes, such as selection, is critical to understanding how phenotypes vary in space and time. Here, we show how evolutionary forces affecting selection, incl...

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Detalles Bibliográficos
Autores principales: Harwood, Michelle P., Alves, Isabel, Edgington, Hilary, Agbessi, Mawusse, Bruat, Vanessa, Soave, David, Lamaze, Fabien C., Favé, Marie-Julie, Awadalla, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9106294/
https://www.ncbi.nlm.nih.gov/pubmed/35559670
http://dx.doi.org/10.1126/sciadv.abl3819